Pizza RestaurantLas Cruces, NM

Domino's – 421 Avenida de Mesilla, Las Cruces

Closed · opens tomorrow 11:00 AM

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Opening hours

Closed · opens tomorrow 11:00 AM

Weekly opening hours of Domino's
Monday	11:00 AM – 11:00 PM
Tuesday	11:00 AM – 11:00 PM
Wednesday	11:00 AM – 11:00 PM
Thursday	11:00 AM – 11:00 PM
Friday	11:00 AM – 11:00 PM
Saturday	11:00 AM – 11:00 PM
Sunday	11:00 AM – 11:00 PM

Local time in Las Cruces: 11:31 PM (MDT). Holiday hours may differ – call (575) 525-0900 to confirm.

Location & directions

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421 Avenida de Mesilla
Las Cruces, NM 88005

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About Domino's

Domino's is a pizza restaurant you'll find at 421 Avenida de Mesilla in Las Cruces, New Mexico. It is one of 164 places to eat and drink we list in Las Cruces.

Domino's is open daily, 11:00 AM – 11:00 PM.

Service options include takeout.

You can reach the team at (575) 525-0900.

Quick facts

Category: Pizza Restaurant
Address: 421 Avenida de Mesilla, Las Cruces, NM 88005
Phone: (575) 525-0900
Hours: Open daily, 11:00 AM – 11:00 PM
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for pizza restaurants and this venue’s opening hours – not live data.

Features & amenities

Service options

Takeout

Reviews

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Frequently asked questions

What are Domino's's opening hours?

Open daily, 11:00 AM – 11:00 PM. Monday: 11:00 AM – 11:00 PM; Tuesday: 11:00 AM – 11:00 PM; Wednesday: 11:00 AM – 11:00 PM; Thursday: 11:00 AM – 11:00 PM; Friday: 11:00 AM – 11:00 PM; Saturday: 11:00 AM – 11:00 PM; Sunday: 11:00 AM – 11:00 PM.

Is Domino's open on Sunday?

Yes, Domino's is open on Sundays: 11:00 AM – 11:00 PM.

Where is Domino's located?

Domino's is located at 421 Avenida de Mesilla, Las Cruces, NM 88005.

What is the phone number of Domino's?

You can call Domino's at (575) 525-0900.

Does Domino's offer delivery or takeout?

Delivery is not listed for Domino's, and takeout is available. Listed service options: takeout.